Biest Cream

In stock
As low as $29.00

How it works

Step 1. No Prescription?

No problem! Choose "I need a prescription" and get treated online by one of our participating providers in 5 minutes. Avoid the hassle and expense of visiting a doctor's office. (not available in LA, RI, VT)

Step 2. You Have a Prescription

Just upload a photo of your prescription after checkout. You can also text us a picture of your prescription or prescription label to 561-619-5169. Only choose "I have a prescription" if you have an actual prescription from your doctor for this specific drug.

Step 3. Your Order Is Processed

Once we receive your prescription from our doctor or yours, we will process your order. We only authorize your credit card at checkout and won't charge your card until we obtain a valid prescription.

Step 4. Your Medication Is Shipped

Your medication is on its way! We ship directly to your door. Never wait in a pharmacy line again!

Low estrogen doesn’t only cause hot flashes, low libido and vaginal dryness. It can also cause skin to thin and trigger acne outbreaks. Topical bioidentical estradiol and estriol may be a great option for women seeking relief from skin conditions also caused by hormonal imbalance. Custom compounded, strength can be adjusted per your prescription.

ERT Options That Fit Your Budget & Unique Medical History

Studies and clinical trials show Hormone Replacement Therapy (HRT) with estrogen can provide much needed relief and health benefits for postmenopausal women. This has empowered more women to step forward and take control of their health.

However, high costs and limited choices remain an obstacle in HRT. This is where custom-compounded bioidentical HRT medications from MintRx is creating new solutions for postmenopausal women. Retail prices for vaginal and topical estrogens are typically hundreds of dollars and may not be covered insurance. Additionally, commercial prescription estrogen formulas have limited options in dosages and delivery methods.

MintRx HRT prescriptions are available in custom formulations and cost as low as $55.

The estrogens used in this formula are bioidentical, which means they are molecular and structural matches to hormones made by the body. Bioidentical hormones are made from diosgenin extracted from plants.

What is the Difference Between Estradiol & Estriol?

The chief female sex hormones are estradiol, estrone and estriol. They are all estrogens (oestrogens) that are naturally created (endogenously) in the body.

Estradiol is the strongest and the most abundant during puberty and a woman's chief reproductive years. It begins to decline around age 35. Estriol (E3) is the weakest of the 3 estrogens and reaches is highest levels during pregnancy.

By the time a woman reaches menopause, estradiol production stops. The only estrogen produced by the body post-menopause is estrone.

Benefits of bHRT With Estradiol And Estriol

Studies show that hormone treatment with estradiol and estriol are effective in providing relief for menopause symptoms caused by lower estrogen levels in the body. Since estriol is weaker than estradiol, some women may prefer a combination of the two estrogens to prevent any risks they may face using estradiol alone. The choice should be discussed with a physician.

What's The Difference Between Estrogen Pills And Topical Creams?

Topical application is absorbed by the body quickly and bypasses the digestive system enhancing the bioavailability of the estrogen. It is capable of increasing estrogen levels within minutes. Relief may begin 1-2 weeks after continued use. Full benefits may take 3-4 weeks. 1

Oral ERT circulates throughout the body and is not targeted. It may not be ideal for women who want the benefits of ERT but do not want estrogen to reach all of the body's organs.

What Is Compounded Medicine?

Compounded medications are made by experts who develop recipes specifically for each patient based on their medical condition and needs. They are prepared in small batches and do not require commercial fillers and preservatives that industrial pharmaceuticals require for a long shelf life.

Another bonus: Custom-compounded medications may cost up to 50% to 75% less than commercial prescriptions.

Mint Rx's expert compounding pharmacists create customized prescriptions from scratch using the same active ingredients found in commercially available prescriptions and obtains medications from FDA-approved sources.

Why Should I Buy Compounded Medicine From MintRx?

With the benefit of personalized medicine at affordable prices, Mint Pharmacy's solutions provide relief for your mind as well as your body. Private, free shipping with the convenience of auto refills and online medical consultations help you continue your HRT.

MintRx is a US certified pharmacy and is accredited by the Pharmacy Compounding Accreditation Board (PCAB).

This product is made by a MintRx partner, a 3rd party licensed, sterile compounding pharmacy.

These statements have not been evaluated by the Food and Drug Administration (FDA). Please consult your physician before starting any exercise or nutritional supplement program before using this or any products if you are pregnant or have a serious medical condition.


1 Krause M, Wheeler TL 2nd, Richter HE, Snyder TE. Systemic effects of vaginally administered estrogen therapy: a review. Female Pelvic Med Reconstr Surg. 2010;16(3):188–195.

This product is custom-compounded cream and available in the following strengths per gram: 0.625gm; 1mg; or 2mg. Each formula contains a balance of 80% estriol and 20% estradiol.

How to use:

Apply estradiol cream to both thighs and calves (lower legs). Apply to skin that is clean, completely dry and not red, irritated, or broken. Do not apply to your breasts.

Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medicine.

If you forget a dose of estradiol cream but remember more than 12 hours before you are scheduled to apply your next dose, apply the missed dose right away. If you remember less than 12 hours before you are scheduled to apply your next dose, skip the missed dose and continue your regular dosing schedule the next day. Do not apply extra estradiol cream to make up for a missed dose.

Tell your doctor if any of these symptoms are severe or do not go away:

  • Headache
  • Breast pain or tenderness
  • Nausea
  • Diarrhea
  • Constipation
  • Gas
  • Heartburn
  • Weight gain or loss
  • Depression nervousness
  • Sleepiness
  • Difficulty falling asleep or staying asleep
  • Changes in sexual desire
  • Back pain
  • Runny nose
  • Cough
  • Flu-like symptoms
  • Hair loss
  • Unwanted hair growth
  • Darkening of the skin on the face
  • Difficulty wearing contact lenses
  • Irritation or redness of the skin at the application area
  • Swelling
  • Redness
  • Burning
  • Irritation, or itching of the vagina vaginal discharge

This product is made by a MintRx partner, a 3rd party licensed, sterile compounding pharmacy.

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