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Obagi Tretinoin Cream 0.025%, 20g


Obagi’s anti-acne prescription powerhouse tretinoin is already converted to the form of Vitamin A that the body creates to regenerate skin cells, heal acne and lighten hyperpigmentation. Applied topically, tretinoin is absorbed deep into the skin where it bolsters the body's skin rejuvenating "workforce."

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Obagi .025% Tretinoin Supercharges Skin Renewal

Obagi tretinoin is proven to treat acne and put the body's ability to produce collagen and new skin cells in high speed. Naturally-derived from Vitamin A, tretinoin is the same acid, all-trans retinoic acid (ATRA), the body creates from Vitamin A. This topically-applied prescription product treats acne vulgaris, melasma, hyperpigmentation, psoriasis and premature aging.

Tretinoin applied on the outside of the skin is absorbed deep within the epidermis where it increases the supply of retinoic acid. Retinoic acid is essential to regenerate skin cells, preserve elastin and boost production of collagen. Collagen keeps the face full and plump, while elastin keep skin firm to prevent sagging.

Because tretinoin, the generic name for Retin-A, is natural and recognized by the body, it is highly effective. Tretinoin is considered to be one of  -- if not the most effective -- anti-aging skin care product available. Results are visible quickly and improve over time.

With continued use, the benefits of tretinoin are sustained. It firms skin, reduces wrinkles, and lightens hyperpigmentation caused by scars, sun damage and melasma. Tretinoin has been used successfully to treat acne for more than 30 years.

How Do I Know What Percent Of Tretinoin To Use? 

Certain medications are available in various strengths because research shows each person may have a unique reaction. The usual recommendation is to begin with the lowest potency. Potency refers to the strength of the medication. In the case of topical tretinoin, strength is measured in concentration.

For newcomers to tretinoin or those with extremely sensitive skin, .025% and .05% tretinoin can be starting points. If either concentration works for you, then you are all set. Overtime you may want to increase the strength if you feel your skin can benefit more.

If the .025% or .05% does not create the desired effect, then a higher strength of generic Retin-A could be the answer. Overall, the idea is to slowly increase the potency, if needed, to find the right strength for you.

Another way to determine the concentration that fits your skin type is to reduce the frequency to 2-3 days a week. You may try this if the side-effects are not tolerable or you just prefer to slow your pace.

Men in general have thicker skin than women, so they are usually advised to jump straight to 0.01% tretinoin, one of the highest potencies.

You may need to use this cream consistently for 6 weeks to 3 months in order to fully experience results. In some cases, acne will temporarily get worse during the course of treatment. This is common and treatment should continue as directed.

More Information
Is a Prescription Product Yes
Use or Effects Anti-Aging, Treat Acne, Fade Hyperpigmentation
Form Cream
Drug Class/Pharmacology Retinoids
Product Specifics

Directions for use: Apply to your face at night 20 minutes after a thorough, gentle cleansing when your skin is completely dry; ensure that your hands are also clean. Spread evenly over your skin, avoiding eye and mouth areas and any open wounds. Wash hands after applying. Use tretinoin in the amounts and frequency directed by your physician. Consult with your doctor if you experience redness, swelling, or irritation that persists.

Safety Information: While using Tretinoin, spend as little time in the sun as possible, use an effective broad spectrum sunscreen, and wear a hat even on cloudy days. Do not use sunlamps or tanning booths, and avoid extreme wind and cold. If you do get a sunburn, stop using Tretinoin until your skin is back to normal. Tretinoin may cause skin irritation. Some patients may get dry, red or peeling skin that requires them to use less medication or use it less often, or stop use either temporarily or altogether. Patients who develop a rash or itchy skin should contact their healthcare provider.

Do not use more Tretinoin, or use it more often, than your doctor has told you because it will not work better and may increase the irritation to your skin. Avoid use of other products that may dry or irritate your skin. The safety and efficacy of Tretinoin have not been established in the treatment of patients younger than 12 years of age (Cream), or in pregnant or nursing women.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

Ingredients: Tretinoin 0.025%, Stearic Acid, Isopropyl Myristate, Polyoxyl 40 Stearate, Stearyl Alcohol, Xanthan Gum, Sorbic Acid, Butylated Hydroxytoluene, Purified Water

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FAQs: Tretinoin .025%

Should I start with .025% tretinoin if I have not used a prescription retinoid before?

.025% strength tretinoin is a good starting point for someone who has not used the prescription retinoid, tretinoin. However, if you do not have sensitive skin and your skin is older or has significant sun damage, wrinkles and hyper-pigmentation, you may consider starting out with tretinoin .05% strength or use the .025% strength tretinoin for just the first few weeks. If after about 3 weeks of using .025% tretinoin, the normal side effects of tretinoin are extremely mild, then your skin can most likely tolerate .05% strength tretinoin. Each individual is different and it's important to determine what your goals are for skin care before making a decision. Tretinoin is available in .025%, .05% and .100% concentration.

What are the side effects of tretinoin?

Common side effects of tretinoin use include increased exfoliation (flaking skin), dry skin that may also itch a lot, some redness and possibly a burning sensation. The side effects should be tolerable and decrease over time. If side effects from tretinoin are not tolerable and do not subside after using it less frequently, then it is recommended to consult a physician. Ways to reduce dryness, redness and irritation include keeping skin hydrated with gentle moisturizers and regulating how often you apply the tretinoin. It is also extremely important anytime you use Retin A (tretinoin) to minimize sun exposure and to always wear a strong broad spectrum sunblock.

At what age should I start using tretinoin?

By age 25, collagen in our skin begins breaking down and new collagen production also slows. Jump forward to our 40s and 50s and the skin cell renewal cycle hits a major wall. Skin cell regeneration can take as long as 45-90 days, compared to teens and 20-somethings where the skin renews itself every few weeks. It is a fact that tretinoin interrupts the cycle of aging and nourishes it with retinoic acid, the same acid the body requires to regenerate skin, produce collagen and rebuild elastin. These are the 3 main components of youthful skin. After considering all of that, define skin care goals. Think about your skin type and your lifestyle. A young person who has significant sun damage (photodamage) from years of sun exposure or hyperpigmentation due to hereditary factors may decide to use tretinoin as early as 18. Someone with sensitive skin may choose to start using the over the counter retinoid, retinol, before stepping up to the prescription grade retinoid, tretinoin. For treating acne, the earliest a child can begin using tretinoin is 12 years of age.

How does tretinoin help relieve psoriasis?

Studies show that tretinoin is effective in treating psoriasis, but why tretinoin reduces the frequency and severity of psoriasis flareups is unknown. Here's the "rub." Tretinoin speeds up skin cell renewal, but fast skin cell growth and turnover is a symptom of psoriasis. Even though it may seem that tretinoin would only exacerbate psoriasis, studies show treatment of psoriasis with tretinoin slows skin cell turnover. This relieves over exfoliation and dry, itchy red patches associated with psoriasis.