Obagi Tretinoin Gel - .05%, 20gm

Obagi Tretinoin Gel - .05%, 20gm

  • In Stock
FSA and HSA Eligible

How it works

Step 1. Answer A Few Questions

We are here to help you look and feel your best. After you complete your checkout. Answer a few questions so that our online doctors can treat you. This is a necessary, 5 minute step for us to complete your order for this prescription product.

Step 2. Your Order Is Processed

Once our online doctors review your answers to learn more about you, we will process your order. We only authorize your credit card at checkout and won't charge your card until we obtain a valid prescription from the online doctor.

Step 3. Your Medication Is Shipped

Your prescription is on its way! We ship directly to your door. Never wait in a pharmacy line or your doctor’s office again!

Please note: We cannot provide telemedicine or ship prescription medication to LA.


Obagi micronized tretinoin gel 0.05% offers the skin-renewing power of Retin A in a milder formula.

  • Fight acne, and reduce the appearance of wrinkles and sun damage with prescription tretinoin.
  • Glycerine, soluble collagen and sodium hyaluronate lock in moisture to reduce irritation.
  • Ideal for beginners to tretinoin or anyone with sensitive skin.
  • Online doctor's visit with Rx valid for 1 year included with purchase.


Obagi Tretinoin Gel 0.05% For Sensitive Skin

Want to treat acne, diminish the appearance of fine lines AND stimulate skin renewal, but can't handle the full strength of Retin A? Then try Obagi's prescription retinoid in a 0.05% gel. It's got all of the anti-aging, acne-fighting power that Retin A is famous for but in a gentler formula.

In addition, to the Vitamin A derivative retinoic acid, Obagi tretinoin gel 0.05% contains:

  • Sodium Hyaluronate - Has all the benefits of hyaluronic acid, with an extra advantage – it’s more easily absorbed than hyaluronic acid. Has the ability to bind and hold onto significant amounts of water.
  • Glycerin - used as a lubricant and humectant. Glycerin attracts water to skin and helps skin to feel softer and smoother.
  • Trolamine - helps calm inflammation.
  • Soluble Collagen,- increases the moisture content of the skin.

What Does Tretinoin Do?

Tretinoin enhances and boosts natural skin renewal in at least 3 major ways.

  • Tretinoin is proven to stimulate new skin cell growth
  • Increase collagen production
  • Rebuild elastin

Tretinoin Gel vs Tretinoin Cream

Tretinoin gels are micronized and delivered in an aqueous formula that enables a slower release of the active ingredient tretinoin (Retin A). A slower release is gentler on skin and may be better tolerated by sensitive skin types. Tretinoin creams are stronger on the skin because they are absorbed into the skin quickly, which causes a fast reaction.

What concentration of tretinoin is right for me?

The usual recommendation for tretinoin use is to begin with the lowest potency. Potency refers to the strength of the medication, also called dosage. In the case of topical tretinoin, strength is measured in concentration or percentage. For newcomers to tretinoin or those with extremely sensitive skin, Obagi's micronized tretinoin gel 0.05% may be ideal. It is time released so it impacts the skin more slowly than tretinoin cream. If your skin can tolerate a stronger potency, .025% or .05% tretinoin cream may be the right starting point.

If you are not sure where to start, begin with the lowest potency and see how your skin reacts. Responses in the skin that seem too strong, could tempt you to drop tretinoin altogether. That decision may be too abrubt. Instead consider reducing the frequency to 2-3 days a week before increasing to daily use.

On the other hand, if the time-released micro Retin A is doing enough, you have the option of upgrading to an entry-level .025% or .05% cream. Give your skin time and gradually find the strength that is right for you.

Men in general have thicker skin than women, so they are usually advised to jump straight to .1% tretinoin, the highest potency.

You may need to use tretinoin consistently for 6 weeks to 3 months in order to fully experience results. In some cases, acne will temporarily get worse during the course of treatment. This is common and treatment should continue as directed.

What are the side effects of tretinoin?

The first stage is called the purge during which new skin cells push the build up of oil and bacteria to the skin's outer layer. Before new skin cells can really be seen, this "interruption" may cause acne to worsen as the skin's layers are "cleaned out." Then, new skin cells cause old skin cells to shed off the surface to make room for the new skin cells. In the beginning the exfoliation may seem extreme. Applying an oil free, gentle moisturizer at least 20 to 45 minutes prior to applying tretinoin can help reduce the appearance of skin flaking.

What's a Good Age To Start Using Tretinoin?

Depending on your skin health and needs, you can begin using tretinoin as early as age 12 to treat acne. A physician will make that decision. For use in anti-aging, 18-25 may be a good starting point depending on your lifestyle. If you have a lot of sun damage, hyperpigmentation from hormone changes or pregnancy or hereditary factors, 18 might work for you. If not, consider an entry level retinoid like Obagi tretinoin gel 0.05% at around 25.

How Does Skin Change As It Ages?

By age 25, collagen in our skin begins breaking down and new collagen production also slows. Jump forward to our 40s and 50s and the skin cell renewal cycle hits a major wall. Skin cell regeneration can take as long as 45-90 days, compared to teens and 20-somethings where the skin renews itself every few weeks. It is a fact that tretinoin interrupts the cycle of aging and nourishes it with retinoic acid, the same acid the body requires to regenerate skin, produce collagen and rebuild elastin.

Obagi tretinoin Gel 0.05% Testimonial

"I have fragile skin. I didn't believe I could use the high strength of Tretinoin, even though I wanted my skin to look its best. After learning about Obagi's Tretinoin Gel from my Dermatologists office, I reluctantly switched from Obagi's Renova (1/4 gram 0.02% nightly) to Obagi's Tretinoin Gel (1/2 gram 0.05% nightly). Now, I wake up in the morning with glowing moist skin, and the best part is I didn't experience any negative side effects. No more red, flaky, irritated skin!" – 42-year-old NuDerm patient.

Before using tretinoin gel:

  • Tell your doctor and pharmacist if you are allergic to tretinoin, fish (if taking Altreno), any other medications, or any of the ingredients in tretinoin gel. Ask your pharmacist for a list of the ingredients..
  • Tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: certain antibiotics such as tetracyclines; antihistamines; diuretics ('water pills'); fluoroquinolones such as ciprofloxacin (Cipro), delafloxacin (Baxdela), gemifloxacin (Factive), levofloxacin (Levaquin), moxifloxacin (Avelox), and ofloxacin; medications for mental illness and nausea; or sulfonamides such as co-trimoxazole (Bactrim, Septra), sulfadiazine, sulfamethizole (Urobiotic), and sulfisoxazole (Gantrisin). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • Tell your doctor if you have or have ever had eczema (a skin disease), actinic keratoses (scaly spots or patches on the top layer of the skin), skin cancer, or other skin conditions.
  • Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while using tretinoin, call your doctor.
  • Plan to avoid unnecessary or prolonged exposure to sunlight or ultraviolet light (tanning beds and sunlamps) and to wear protective clothing, sunglasses, and sunscreen. Tretinoin may make your skin sensitive to sunlight or ultraviolet light.
  • You should know that weather extremes, such as wind and cold, may be particularly irritating.

What should I do if I forget a dose?

Apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not apply extra cream, lotion, or gel to make up for a missed dose.

Tretinoin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • Warmth or slight stinging of the skin
  • Lightening or darkening of the skin
  • Red, scaling skin
  • Increase in acne sores
  • Swelling, blistering, or crusting of the skin
  • Dryness, pain, burning, stinging, peeling, redness, or flaky skin at the treatment area

Some side effects can be serious. If you experience any of these symptoms call your doctor immediately:

  • Itching
  • Hives
  • Pain or discomfort at the treatment area

Tretinoin may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

Directions for use: Apply at bedtime and wear sunscreen when exposed to sun. Before applying, wash your face and wait at least 20 minutes for your face to dry. Wash your hands thoroughly and apply a pea size amount of the cream. Gently smooth on your face until it disappears. Do not rub into your face and avoid getting in eyes and mouth. Wash hands immediately after applying.

Use tretinoin regularly as directed by your dermatologist/physician to get the most benefit.

Tretinoin gel is the active ingredient in Retin-A Gel Micro and an FDA-approved generic equivalent.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online http://www.fda.gov/Safety/MedWatch or by phone (1-800-332-1088).

This Product Is FSA/HSA Eligible

Score! You may purchase this product by simply using your FSA/HSA debit card at checkout.

How Do I Use My FSA/HSA Debit Card At MintRx?

  • Place all of your qualifying items in your cart. All MintRx prescriptions, including our custom-made medications, are approved for FSA and HSA purchase. Also, use your FSA/HSA debit for qualified over-the-counter items such as at-home lab tests and acne treatments. We've marked each FSA/HSA eligible item with a badge.
  • Make your purchase using your debit card.

What If I Want To Purchase Items That Are Not FSA/HSA Approved?

If you are also buying non-eligible FSA/HSA items, you are required to make a separate transaction.

What Are FSA and HSA Accounts?

FSA's and HSA's are federal programs that make it easy for you to enjoy significant tax benefits for qualified out-of-pocket medical expenses. Each program works a little differently but with each you avoid federal, state and local income taxes on any funds that you use for qualified medical expenses.

FSA tax benefits are administered by your job. Funds in an amount that you decide —within the program limits—are withdrawn from your paycheck without any payroll tax deductions.

Tax benefits with an HSA may be administered that way but there are also other options.

How Do I Use My FSA/HSA Funds?

You can use a pre-loaded debit card or get reimbursed from your FSA or HSA account after you make your purchase or a combination of both methods.