PT-141 Bremelanotide Injection
Find out why FDA-approved PT-141 (Bremelanotide) is helping restore women's sexual satisfaction and is showing promise as a treatment for Erectile Dysfunction.*
- In clinical trials, women who used bremelanotide, the active ingredient in Vyleesi, reported their sexual enjoyment more than doubled!
- Some clinical studies showed that PT-141 treated ED in men and significantly improved erections in men without ED.*
The peptide PT-141 gets your brain in the game by acting on neurotransmitters that impact libido and sexual function. PT-141 is not a PDE5 inhibitor like Viagra (Sildenafil) and Cialis (Tadalafil) and shows promise for men and women who have not had success with those treatments. Save money and receive personalized and private treatment with MintRx's custom-compounded PT-141.
Please note: We cannot provide telemedicine for ED in LA, MN and SC.
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Ask About Compounded "Vyleesi" For Men And Women
Find out PT-141, also known as bremelanotide, helps restore women's sexual satisfaction and shows promise as a treatment for Erectile Dysfunction.*
PT-141 is the active ingredient in Vyleesi, the FDA-approved drug to treat Hypoactive Sexual Desire Disorder (HSDD) in women, but the peptide's affect was originally discovered in men. While researching a drug to darken skin, researchers noticed that men got spontaneous erections.
How Does PT-141/Vyleesi Work?
It is not known exactly how PT-141 can cause erections in men and increase women's libido and sexual satisfaction but it appears that it gets your brain in the game by acting on neurotransmitters that impact libido and sexual function.
In clinical trials, women who used bremelanotide reported their sexual enjoyment more than doubled! Some clinical studies showed that PT-141 treated ED in men and significantly improved erections in men without ED.*
PT-141 is not a PDE5 inhibitor like Viagra (Sildenafil) and Cialis (Tadalafil) and shows promise for men and women who have not had success with those treatments.
An article published in The Journal Nature on the effect of PT-141 on men with ED and men without ED, showed the effects of PT-141 were "clinically significant". Both groups achieved erections when using the PT-141 intranasally.
Studies on intranasal administration of PT-141 reported the spray has the same impact as the injection.
What Is PT-141?
PT-141 is a peptide drug that affects neurotransmitters in the brain called melanocortins. It is an agonist at melanocortin receptors. This means it activates the receptors, causing a response. Melanocortin receptors control sexual function, impact appetite, and immunity, among other physiologic actions.
PT-141 offers promise treating sexual dysfunction in men and women who do not have success with the PDE5 inhibitors Viagra (sildenafil) and Cialis (tadalafil) or can't take sildenafil or tadalafil for health reasons.
What Is the Difference Between PT-141 and Cialis and Viagra?
PT-141 works in the brain, while Cialis (tadalafil) and Viagra (sildenafil) increase blood flow to the penis.
How Do PDE5 Inhibitors Work?
Inhibiting, or blocking, the enzyme phosphodiesterase 5 (PDE5), slows the breakdown of the molecule cGMP. With cGMP still active, the smooth muscles in the penis relax or stay relaxed longer. When the muscles relax, blood vessels open to increase blood flow. This is called vasodilation.
Studies show PDE5 inhibitors may have the same effect in premenopausal 2 and postmenopausal women.3 They increase blood flow to the vagina and clitoris, which boosts libido, increases vaginal lubrication and improves sexual satisfaction. 2,3
Having these medications that function differently expands sexual dysfunction treatment opportunities for men and women.
1 Diamond, L., Earle, D., Rosen, R. et al. Double-blind, placebo-controlled evaluation of the safety, pharmacokinetic properties and pharmacodynamic effects of intranasal PT-141, a melanocortin receptor agonist, in healthy males and patients with mild-to-moderate erectile dysfunction. Int J Impot Res 16, 51–59 (2004). https://doi.org/10.1038/sj.ijir.3901139
2 Caruso, Salvatore & Intelisano, Giorgia & Lupo, Lorenzo & Agnello, Carmela. (2001). Premenopausal women affected by sexual arousal disorder treated with sildenafil: A double-blind, cross-over, placebo-controlled study. BJOG : an international journal of obstetrics and gynaecology. doi: 108. 623-8. 10.1016/S0306-5456(00)00143-1
3 Alatas E, Yagci AB. The effect of sildenafil citrate on uterine and clitoral arterial blood flow in postmenopausal women. MedGenMed. 2004;6(4):51. Published 2004 Oct 13. The effect of sildenafil citrate on uterine and clitoral arterial blood flow in postmenopausal women.
This product is made by a MintRx partner, a 3rd party licensed, sterile compounding pharmacy.
These statements have not been evaluated by the Food and Drug Administration (FDA). Please consult your physician before starting any exercise or nutritional supplement program before using this or any products if you are pregnant or have a serious medical condition.
Why Buy Compounded Medicine From MintRx?
With the benefit of personalized medicine at affordable prices, MintRx's solutions provide relief for your mind as well as your body. Private, free shipping with the convenience of auto refills and online medical consultations help you take control of your health.
MinRx is a US certified pharmacy and is accredited by the Pharmacy Compounding Accreditation Board (PCAB). This product is made by a MintRx partner, a 3rd party licensed, sterile compounding pharmacy.
*These statements have not been evaluated by the Food and Drug Administration (FDA). Please consult your physician before starting any exercise or nutritional supplement program before using this or any products if you are pregnant or have a serious medical condition.
WARNING: This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.
Bremelanotide is used to treat low sexual desire in women who have not gone through menopause and have not had low sexual desire in the past. Bremelanotide is not for use in men traditionally, however, physicians are prescribing it for men for off-label use. Bremelanotide is not for sexual desire issues related to health and/or relationship problems, nor for mental illness, and it is contraindicated for the following conditions:
- Heart disease
- High blood pressure
- 18 years or younger
- Kidney disease
- Liver disease
Bremelanotide is harmful to an unborn baby. Stop using this medication and tell your doctor right away if you become pregnant. Do not breastfeed.
WHAT HAPPENS IF I MISS A DOSE? Since Bremelanotide is taken when needed, it does not have a daily dosing schedule.
WHAT HAPPENS IF I OVERDOSE? Seek emergency medical attention or call the Poison Helpline at 1-800-222-1222.
SIDE EFFECTS Get emergency help if you show signs of an allergic reaction:
- Difficulty breathing
- Swelling of the tongue or throat
- Slow heartbeat
- Severe headache
- Blurred vision
- High blood pressure
- Hot flashes
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