Before taking rosuvastatin:
- Tell your doctor and pharmacist if you are allergic to rosuvastatin, any other medications, or any of the ingredients in rosuvastatin tablets or capsules.
- Ask your pharmacist for a list of the ingredients.
- Tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin); colchicine (Colcrys); cimetidine (Tagamet); cyclosporine (Neoral, Sandimmune); eltrombopag (Promacta); ketoconazole (Nizoral); other medications for high cholesterol such as fenofibrate (Tricor), gemfibrozil (Lopid), and niacin (Niaspan, Niacor); certain HIV protease inhibitors including atazanavir (Reyataz) taken with ritonavir (Norvir), and lopinavir and ritonavir (Kaletra); and spironolactone (Aldactone). Many other medications may also interact with rosuvastatin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- If you are taking aluminum and magnesium hydroxide antacids (Mylanta, Maalox), take them at least 2 hours after rosuvastatin.
- Tell your doctor if you have liver disease. Your doctor will order laboratory tests to see how well your liver is working even if you do not think you have liver disease. Your doctor will probably tell you not to take rosuvastatin if you have liver disease or if the tests show that you may be developing liver disease.
- Tell your doctor if you are Asian, if you drink more than 2 alcoholic beverages daily, if you are 65 years of age or older, if you have ever had liver disease, or if you have or have ever had seizures, muscle aches or weakness, low blood pressure, or kidney or thyroid disease.
- Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while you are taking rosuvastatin. Talk to your doctor about birth control methods that you can use during your treatment. If you become pregnant while taking rosuvastatin, call your doctor immediately. Rosuvastatin may harm the fetus.
Do not breastfeed while taking rosuvastatin.
If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking rosuvastatin. If you are hospitalized due to serious injury or infection, tell the doctor who treats you that you are taking rosuvastatin.
Ask your doctor about the safe use of alcoholic beverages while you are taking rosuvastatin. Alcohol can increase the risk of serious side effects.
Eat a low-fat, low-cholesterol diet. Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian. You can also visit the National Cholesterol Education Program (NCEP) website for additional dietary information at http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.
If you forget a dose, take the missed dose as soon as you remember it. However, if it is less than 12 hours before your next dose is scheduled, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Rosuvastatin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- stomach pain
- difficulty falling asleep or staying asleep
- joint pain
- memory loss or forgetfulness
Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical help:
- muscle pain tenderness, or weakness
- lack of energy
- chest pain
- yellowing of the skin or eyes
- dark colored urine
- pain in the upper right part of the abdomen
- extreme tiredness weakness
- unusual bleeding or bruising
- loss of appetite
- flu-like symptoms
- difficulty breathing or swallowing
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. Visit http://www.upandaway.org for more information.
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Keep all appointments with your doctor and the laboratory. Your doctor may order lab tests during your treatment, especially if you develop symptoms of liver damage.
Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking rosuvastatin.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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