Simvastatin - Generic Zocor
Priced Per Pill
Common 30-Day Supply: 60
If you have or are at risk for heart disease, your doctor may prescribe simvastatin, generic Zocor, in combination with a diet, weight-loss, and an exercise program. You may be at risk for heart disease if you have high levels of low-density lipoprotein (LDL) "bad cholesterol" or elevated fatty substances (triglycerides) in your blood. Simvastatin may also be prescribed to children 10-17 years old who have high both cholesterol and triglycerides due to the hereditary condition heterozygous hypercholesterolemia. Heterozygous hypercholesterolemia causes cholesterol due to the body's inability to remove cholesterol from the blood. Simvastatin belongs to the drug class HMG-CoA reductase inhibitors (statins). Statins work by slowing the body's production of cholesterol, which can prevent atherosclerosis. Atherosclerosis, also called blocked or hardened arteries, develop when fat and cholesterol build up on arterial walls and stop or slow blood flow to the heart and other parts of the body.
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Before taking simvastatin:
- tell your doctor and pharmacist if you are allergic to simvastatin, any other medications, or any of the ingredients in simvastatin tablets or oral suspension. Ask your doctor or pharmacist for a list of the ingredients.
- tell your doctor if you are taking antifungal medications such as itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil) and voriconazole (Vfend); clarithromycin (Biaxin, in Prevpac); cobicistat-containing medications (Stribild); cyclosporine (Gengraf, Neoral, Sandimmune); danazol; erythromycin (E.E.S., E-Mycin, Erythrocin); gemfibrozil (Lopid); HIV protease inhibitors such as atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), indinavir (Crixivan), lopinavir (in Kaletra), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), saquinavir (Invirase), and tipranavir (Aptivus); nefazodone; telaprevir (Incivek); and telithromycin (Ketek). Your doctor will probably tell you not to take simvastatin if you are taking these medications.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: amiodarone (Cordarone, Pacerone); amlodipine (Norvasc, in Caduet, in Lotrel); anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); colchicine (Colcrys); digoxin (Digitek, Lanoxicaps, Lanoxin); diltiazem (Cardizem, Dilacor, Tiazac); dronedarone (Multaq); other cholesterol-lowering medications such as fenofibrate (Tricor), lomitapide (Juxtapid), and niacin (nicotinic acid, Niacor, Niaspan); ranolazine (Ranexa); and verapamil (Calan, Covera, Isoptin, Verelan). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Other medications may also interact with simvastatin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
- tell your doctor if you have liver disease. Your doctor will order blood tests to see how well your liver is working even if you do not think you have liver disease. Your doctor will probably tell you not to take simvastatin if you have liver disease or if the tests show that you may be developing liver disease.
- tell your doctor if you drink more than two alcoholic beverages per day, if you are 65 years of age or older, or if you are Asian, especially if you are Chinese. Also tell your doctor if you have or have ever had an underactive thyroid gland, diabetes, seizures, muscle aches or weakness, low blood pressure, or kidney disease.
- tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant during your treatment with simvastatin. Talk to your doctor about birth control methods that will work for you. If you become pregnant while taking simvastatin, stop taking simvastatin and call your doctor immediately. Simvastatin can harm the fetus.
- tell your doctor if you are breastfeeding. You should not breastfeed while you are taking simvastatin.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking simvastatin. If you are hospitalized due to serious injury or infection, tell the doctor who treats you that you are taking simvastatin.
- ask your doctor about the safe use of alcoholic beverages while you are taking simvastatin. Alcohol can increase the risk of serious side effects.
Eat a low-fat, low-cholesterol diet. Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian. You can also visit the National Cholesterol Education Program (NCEP) website for additional dietary information http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf
Avoid drinking grapefruit juice while taking simvastatin.
If you miss a dose, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue the regular dosing schedule. Do not take a double dose to make up for a missed one.
Simvastatin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- stomach pain
- memory loss or forgetfulness
- itchy or red skin
Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical help.
- muscle pain, tenderness, or weakness with or without fever or lack of energy
- dark red urine
- decreased urination
- lack of energy, tiredness, or weakness
- loss of appetite
- pain in the upper right part of the stomach
- yellowing of the skin or eyes
- dark colored urine
- fever or chills
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- difficulty breathing or swallowing
- joint pain
- sensitivity to light
This medication may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online http://www.fda.gov/Safety/MedWatch
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the tablets at room temperature and away from excess heat and moisture (not in the bathroom). Store the suspension at room temperature. Do not freeze or refrigerate the suspension. Be sure to use the suspension within 30 days of opening the bottle and discard any remaining medication after 30 days.
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. Visit http://www.upandaway.org for more information.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website http://goo.gl/c4Rm4p.
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests during your treatment, especially if you develop symptoms of liver damage.